Stem Cell for Beauty
In general terms, stem cells are the main cells found in the human body and capable of being transformed into body cells of various kinds. They have infinite proliferation and differentiation capacity. Wherever there is a bruising or a need for repair, they go there to become the required cell type and repair the damage.
The ratio of stem cells and the ability to transform into different structures is the highest in embryonic, fetal tissues and later in infants, but decreases as age progresses. It is for this reason that, wound healing in adults and elderly becomes increasingly difficult, and organ-tissue failure related diseases begin to appear. Because the lower the ratio of stem cells per total cell, the slower the tissue-organ recovery.
Similarly, depending on the aging of the skin, dryness, wrinkles, subcutaneous tissue thinning and smearing begin to be seen. Skin texture begins to loosen and sag. So how can stem cells help us on this issue?
If the person does not have any stocked source such as stored cord blood-texture, which is from infancy, which has a longer life span (long telomere) and a higher reproductive capacity; it is clear that we need to make use of the available resources more efficiently.
The most common stem cell sources used for cosmetic purposes in the world today are skin and fat tissue. In some ecoles, such as German and Swiss, tissue extracts from lamb fetuses are used, but this is not widespread worldwide.
In order to obtain stem cells from the skin, a small biopsy from the back of the ear is taken and put into nutrient fluid. The reason why this region is preferred is that it is naturally preserved from the sun and therefore the biological age is smaller than the face. The stem cells are separated by putting the tissue through enzymatic-physical processes in a laboratory with GMP standards. It is planted in plastic containers containing medium, waiting for it to multiply. The proliferating cells are collected and divided into new containers, again expected to multiply. This process is repeated four or five times to multiply the cells. The process lasts for one to one-and-a-half months.
Almost all of these cells will turn into fibroblast structure, either during production or after application to the skin. Fibroblasts are the basic cells responsible for the synthesis of collagen in the skin. In addition to collagen, elastic fibers and hyaluronic acid are produced by fibroblasts. The fibroblast cells in the skin play a leading role in wound healing and tissue repair. Decrease in these cells with age progression is the main cause of treatment. Following the replication process, cells are subcutaneously administered with the help of fine-tipped needles to increase the number of fibroblasts per millimeter, thereby activating the skin.
Obtaining of stem cells from fat tissue, is mainly applied to people who will have liposuction done. Stem cells are mostly separated from fat tissue taken from the abdomen or upper leg, with the help of a special machine. The feature of this method is that the cells can be taken and applied to the required region at the same time, while the patient is under the general anesthesia. If the area to be applied is large, these cells can also be reproduced. In this case, there will again be a period of time between obtaining and application.
For a successful treatment (e.g., in the face area), it is targeted to deliver about 200-300 million cells, even at intervals. Usually two sessions, two to three weeks apart are sufficient. Since the cells applied to the skin are the person’s own cells and continue to live, the obtained state of wellness lasts longer.
During the application, PRP (Platelet Rich Plasma) can be given together with the stem cells to provide support of various magnifier, enhancer secretions. For this purpose, 10cc of blood taken from the person is turned in the centrifuge, separating the plasma part and the part of the red blood cells. The part that contains thrombocytes, which provide blood coagulation, is taken and used. Likewise, using a filler such as hyaluronic acid for very deep and settled wrinkles will increase local success.